Description

2-Pyrimidinamine, 4,6-Difluoro-5-Methyl- (9Ci) is a high-purity fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which imparts specific reactivity and properties essential for creating complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry and agrochemical research.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the difluoro-methyl pyrimidine core contributes to biological activity.
• Material Science Research: Employed as a precursor for the synthesis of specialized fluorinated polymers or liquid crystals with unique electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects requiring a specific, fluorinated heterocyclic scaffold.

Basic Information

Product Name	2-Pyrimidinamine, 4,6-Difluoro-5-Methyl- (9Ci)
CAS No.	18260-79-2
Molecular Formula	C5H5F2N3
Molecular Weight	145.11 g/mol
Synonyms	4,6-Difluoro-5-methylpyrimidin-2-amine; 5-Methyl-4,6-difluoropyrimidin-2-amine; 2-Amino-4,6-difluoro-5-methylpyrimidine; 4,6-Difluoro-5-methyl-2-pyrimidinamine; 18260-79-2; 5-Methyl-4,6-difluoro-2-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine, 4,6-Difluoro-5-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic). Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.