Description

2-(Hydroxymethyl)-2-(2-Hydroxybenzylideneamino)-1,3-Propanediol is a specialized organic compound featuring a salicylaldehyde-derived imine (Schiff base) structure integrated with a propanediol backbone. This molecular architecture is significant for its potential as a versatile chelating agent and building block in coordination chemistry and material science. It is primarily needed by researchers and manufacturers in the fields of advanced material synthesis, pharmaceutical intermediates, and specialty chemical catalysis.

Application

• Metal Chelation & Catalyst Precursor: Acts as a ligand for complexing transition metals (e.g., Cu, Ni, Zn) in homogeneous catalysis and material synthesis.
• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Polymer Modification: Used as a functional monomer or cross-linking agent to impart specific properties to polymeric materials.
• Analytical Chemistry: Employed in the development of selective sensors and indicators for metal ion detection.
• Corrosion Inhibition: Investigated for use in formulating protective coatings and additives for metal surfaces.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct more complex nitrogen- and oxygen-containing molecules.

Basic Information

Product Name	2-(Hydroxymethyl)-2-(2-Hydroxybenzylideneamino)-1,3-Propanediol
CAS No.	18212-81-2
Molecular Formula	C11H15NO5
Molecular Weight	241.24 g/mol
Synonyms	2-(Hydroxymethyl)-2-[(2-hydroxyphenyl)methylideneamino]propane-1,3-diol; N-Salicylidene-tris(hydroxymethyl)aminomethane; Salicylaldehyde-Tris Derivative; Schiff Base of Tris(hydroxymethyl)aminomethane and Salicylaldehyde; THAM-Salicylaldehyde Adduct; 1,3-Propanediol, 2-(hydroxymethyl)-2-[(2-hydroxyphenyl)methylene]amino]-; 18212-81-2
EINECS	Contact for details

Quality Control

Our production of 2-(Hydroxymethyl)-2-(2-Hydroxybenzylideneamino)-1,3-Propanediol adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. While typically supplied in research or technical grade, specifications can be tailored to meet project-specific requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.