Description

5-Oxo-1-Phenyl-Pyrrolidine-2-Carboxylic Acid is a high-purity pyrrolidone derivative and a versatile chiral building block in organic synthesis. This compound matters for its role as a critical intermediate in the development of advanced pharmaceuticals and fine chemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its pyrrolidone core structure.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, dyes, and performance materials requiring specific stereochemistry.
• Academic & Industrial Research: Employed in medicinal chemistry programs and as a standard for analytical method development.
• Peptidomimetic Development: The scaffold is valuable for creating peptide analogs and protease inhibitors in drug design.

Basic Information

Product Name	5-Oxo-1-Phenyl-Pyrrolidine-2-Carboxylic Acid
CAS No.	18133-18-1
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	1-Phenyl-5-oxopyrrolidine-2-carboxylic acid; 1-Phenyl-2-pyrrolidone-5-carboxylic acid; 5-Oxo-1-phenyl-2-pyrrolidinecarboxylic acid; 2-Pyrrolidinecarboxylic acid, 5-oxo-1-phenyl-; NSC 163022; 1-Phenyl-5-oxo-DL-proline; 5-Oxo-1-phenylproline; (RS)-5-Oxo-1-phenylpyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-Phenyl-Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.