Description

2,5-Dimethoxyphenylacetonitrile is a versatile aromatic nitrile building block characterized by its dimethoxy-substituted phenyl ring. This compound matters for its role as a key synthetic intermediate in the production of complex organic molecules, offering a reactive nitrile group for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those with complex aromatic or heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where the dimethoxyphenyl moiety is a key pharmacophore.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Investigated as a building block for π-conjugated systems in the development of organic semiconductors and light-emitting materials.
• Dye and Pigment Intermediate: Employed in the synthesis of advanced dyes and functional pigments due to its electron-donating methoxy groups.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and cyanation reactions.

Basic Information

Product Name	2,5-Dimethoxyphenylacetonitrile
CAS No.	18086-24-3
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(2,5-Dimethoxyphenyl)acetonitrile; 2-(2,5-Dimethoxyphenyl)acetonitrile; 2,5-Dimethoxybenzyl cyanide; α-Cyano-2,5-dimethoxytoluene; Benzeneacetonitrile, 2,5-dimethoxy-; 18086-24-3; 2,5-Dimethoxybenzyl nitrile
EINECS	Contact for details

Quality Control

Our 2,5-Dimethoxyphenylacetonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.