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Tris(Trimethylsilylmethyl)Phosphine CAS NO 18077-42-4


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CAS No.:18077-42-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Tris(trimethylsilylmethyl)phosphine is a highly reactive organophosphorus compound featuring three trimethylsilylmethyl groups bonded to a central phosphorus atom. This structure makes it a versatile and powerful reagent in advanced synthetic chemistry, particularly valued for its role as a phosphine ligand precursor and a source of nucleophilic phosphorus. It is essential for researchers and process chemists in the fine chemical and pharmaceutical sectors who require sophisticated building blocks for catalysis and complex molecule synthesis. Its unique reactivity profile enables critical transformations in the development of new materials and active pharmaceutical ingredients (APIs).

Application

  • As a key precursor for the synthesis of specialized phosphine ligands used in homogeneous catalysis, including cross-coupling reactions.
  • As a nucleophilic phosphorus source in the preparation of novel organophosphorus compounds for material science applications.
  • In the research and development of advanced pharmaceutical intermediates where precise phosphorus incorporation is required.
  • For the synthesis of phosphorus-containing polymers and specialty chemicals with tailored properties.
  • As a reagent in academic and industrial research exploring new methodologies in main-group element chemistry.

Basic Information

Product Name Tris(trimethylsilylmethyl)phosphine
CAS No. 18077-42-4
Molecular Formula C12H33PSi3
Molecular Weight 292.63 g/mol
Synonyms Tris((trimethylsilyl)methyl)phosphine; Phosphinotris(methylene(trimethylsilane)); Tris(trimethylsilylmethyl)phosphane; P(CH2SiMe3)3; (Trimethylsilylmethyl)phosphine, tris-; Tris(trimethylsilylmethyl)phosphorus
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Quality Control

Our Tris(trimethylsilylmethyl)phosphine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analysis, including NMR spectroscopy and chromatographic methods, to verify identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly sensitive nature, this material is Easily oxidized (store under inert atmosphere) and Hygroscopic (moisture-sensitive). It must be stored under an inert gas atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Handle and open containers only in a controlled, moisture-free environment.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (NMR) Conforms to structure
Purity (GC or NMR) ≥ 95%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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