Description

Methyl 5-Bromo-2-Hydroxy-3-Iodobenzenecarboxylate is a high-purity, multi-halogenated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocycles and active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and plant growth regulators due to its halogenated phenolic structure.
• Material Science: Used in the synthesis of advanced organic electronic materials, including liquid crystals and charge-transport molecules.
• Catalyst & Ligand Development: The halogen and hydroxyl groups provide handles for creating sophisticated chelating ligands for transition metal catalysis.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of molecular imaging agents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	Methyl 5-Bromo-2-Hydroxy-3-Iodobenzenecarboxylate
CAS No.	18071-51-7
Molecular Formula	C8H6BrIO3
Molecular Weight	356.94 g/mol
Synonyms	Methyl 5-bromo-2-hydroxy-3-iodobenzoate; 5-Bromo-2-hydroxy-3-iodobenzoic acid methyl ester; Benzoic acid, 5-bromo-2-hydroxy-3-iodo-, methyl ester; 3-Iodo-5-bromo-2-hydroxybenzoic acid methyl ester; Methyl 3-iodo-5-bromo-2-hydroxybenzoate; 2-Hydroxy-3-iodo-5-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Hydroxy-3-Iodobenzenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring material that meets GMP or other stringent regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.