Description

[S,(+)]-5-[(Z)-Ethylidene]-2-Hydroxy-2-Methyl-3-Methylenehexanedioic Acid is a high-purity, stereochemically defined organic acid derivative of significant interest in advanced chemical synthesis. Its unique chiral and unsaturated structure makes it a valuable specialty building block for the development of complex molecules. This compound is primarily sought by pharmaceutical R&D and fine chemical industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific stereochemistry.
• Asymmetric Synthesis: Utilized as a sophisticated building block in catalytic and stoichiometric asymmetric synthesis to introduce complex molecular fragments.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and performance materials where its specific functional groups are critical.
• Academic and Industrial Research: Used in chemical biology and medicinal chemistry programs to explore structure-activity relationships and develop new molecular entities.

Basic Information

Product Name	[S,(+)]-5-[(Z)-Ethylidene]-2-Hydroxy-2-Methyl-3-Methylenehexanedioic Acid
CAS No.	18003-06-0
Molecular Formula	C10H14O5
Molecular Weight	214.22 g/mol
Synonyms	(S)-5-[(Z)-Ethylidene]-2-hydroxy-2-methyl-3-methylidenehexanedioic acid; (S)-(+)-5-[(Z)-Ethylidene]-2-hydroxy-2-methyl-3-methylenehexanedioic acid; (S)-5-(1-Z-Ethylidene)-2-hydroxy-2-methyl-3-methylidenehexanedioic acid; 2-Hydroxy-2-methyl-3-methylene-5-(1Z-ethylidene)hexanedioic acid, (S)-; (S)-2-Hydroxy-2-methyl-3-methylene-5-[(Z)-ethylidene]hexanedioic acid; A chiral hexanedioic acid derivative; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our production of [S,(+)]-5-[(Z)-Ethylidene]-2-Hydroxy-2-Methyl-3-Methylenehexanedioic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chiral purity and chemical integrity, meeting the exacting standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to heat and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.