Description

2-(Trimethylsiloxy)Benzoic Acid Methyl Ester is a specialized organosilicon intermediate with a protected phenolic hydroxyl group. This compound is valued for its role in synthetic organic chemistry, particularly in the protection and subsequent deprotection of sensitive functional groups during multi-step synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and advanced materials sectors for developing active pharmaceutical ingredients (APIs) and novel silicon-containing compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, especially where phenolic protection is required.
• Organosilicon Chemistry: Serves as a precursor for the preparation of various silyl ethers and other silicon-based reagents.
• Chemical Synthesis: Used as a protecting group agent for phenols in multi-step organic synthesis to prevent unwanted side reactions.
• Material Science Research: Employed in the development of novel silicone polymers and hybrid organic-inorganic materials.
• Agrochemical Synthesis: Intermediate in the production of certain specialty pesticides and herbicides requiring silicon functionalities.

Basic Information

Product Name	2-(Trimethylsiloxy)Benzoic Acid Methyl Ester
CAS No.	18001-14-4
Molecular Formula	C11H16O3Si
Molecular Weight	224.33 g/mol
Synonyms	Methyl 2-(Trimethylsiloxy)benzoate; Methyl Salicylate Trimethylsilyl Ether; 2-(Trimethylsilyloxy)benzoic Acid Methyl Ester; O-Trimethylsilylsalicylic Acid Methyl Ester; Salicylic Acid Methyl Ester Trimethylsilyl Ether; Methyl O-Trimethylsilylsalicylate; 2-[(Trimethylsilyl)oxy]benzoic Acid Methyl Ester; Benzoic acid, 2-(trimethylsiloxy)-, methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality parameters include purity by GC/HPLC, identity confirmation by FT-IR and NMR, and control of key impurities. Certificates of Analysis (COA) are available upon request, detailing all analytical results. We adhere to a cGMP-compliant quality management system for products intended for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.