Description

Ethyl 4-Ethyl-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, versatile tetrahydropyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its role as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate and scale new therapeutic and specialty chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of dihydropyrimidinone (DHPM) based drug candidates, which exhibit a wide range of biological activities.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the bioactive properties of the tetrahydropyrimidine core.
• Fine Chemical Synthesis: Acts as a versatile precursor for creating complex heterocycles, dyes, and functional materials in specialty chemical manufacturing.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including multicomponent reactions and catalyst development.
• Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Ethyl 4-Ethyl-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	17994-57-9
Molecular Formula	C10H16N2O3
Molecular Weight	212.25 g/mol
Synonyms	Ethyl 4-ethyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; 5-Carbethoxy-4-ethyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 4-Ethyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester; Biginelli compound derivative; DHPM derivative; 5-Ethoxycarbonyl-4-ethyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one; Ethyl 4-ethyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Ethyl-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.