Description

2-[4-(4-Fluorophenyl)-1,3-Thiazol-2-Yl]Acetonitrile is a high-value pharmaceutical intermediate and versatile organic building block featuring a fluorinated phenylthiazole core. Its molecular structure makes it a critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity. This compound is essential for research and development chemists, process scale-up engineers, and manufacturers within the global pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and anti-infective research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides that leverage the fluorinated thiazole moiety for enhanced efficacy.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.

Basic Information

Product Name	2-[4-(4-Fluorophenyl)-1,3-Thiazol-2-Yl]Acetonitrile
CAS No.	17969-48-1
Molecular Formula	C11H7FN2S
Molecular Weight	218.25 g/mol
Synonyms	2-(4-(4-Fluorophenyl)thiazol-2-yl)acetonitrile; (4-(4-Fluorophenyl)-2-thiazolyl)acetonitrile; 2-(4-(p-Fluorophenyl)-1,3-thiazol-2-yl)acetonitrile; 4-(4-Fluorophenyl)-2-thiazoleacetonitrile; 2-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]ethanenitrile; Acetonitrile, 2-[4-(4-fluorophenyl)-2-thiazolyl]-; 17969-48-1
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Fluorophenyl)-1,3-Thiazol-2-Yl]Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.