Description

1-Cyano-1,2-Dihydroisoquinoline-2-Carboxylic Acid Ethyl Ester is a versatile heterocyclic building block and key synthetic intermediate of significant interest in advanced organic synthesis. Its core isoquinoline scaffold and functionalized ester group make it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Reagent: Used in the construction of nitrogen-containing heterocycles, which are prevalent in many bioactive molecules and functional materials.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with novel modes of action.
• Material Science: Investigated for the synthesis of organic ligands and functional polymers with specific electronic or photophysical properties.
• Academic & R&D: Employed in methodological research and as a standard in analytical chemistry for method development and validation.

Basic Information

Product Name	1-Cyano-1,2-Dihydroisoquinoline-2-Carboxylic Acid Ethyl Ester
CAS No.	17954-22-2
Molecular Formula	C₁₃H₁₂N₂O₂
Molecular Weight	228.25 g/mol
Synonyms	Ethyl 1-cyano-1,2-dihydroisoquinoline-2-carboxylate; 2-Carbethoxy-1-cyano-1,2-dihydroisoquinoline; 1,2-Dihydro-1-cyano-2-ethoxycarbonylisoquinoline; 1-Cyano-2-ethoxycarbonyl-1,2-dihydroisoquinoline; 1-Cyano-1,2-dihydro-2-ethoxycarbonylisoquinoline; Ethyl 1-cyano-3,4-dihydroisoquinoline-2(1H)-carboxylate; 17954-22-2
EINECS	Contact for details

Quality Control

Our production of 1-Cyano-1,2-Dihydroisoquinoline-2-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, and NMR. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.