Description

(8α)-14β-Hydroxy-3-Methoxy-D-Homoestra-1,3,5(10),9(11)-Tetren-17A-One is a high-purity, specialized steroidal intermediate with a complex, modified estrane backbone. This compound matters for its role as a critical building block in advanced pharmaceutical synthesis, particularly for the development of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in steroid chemistry, hormone research, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for investigating structure-activity relationships (SAR) in steroid-based therapeutics.
• Hormone Analog Synthesis: Serves as a starting material for creating modified estrogen or related hormone analogs for biological evaluation.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of complex steroid molecules.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Potential use in studying steroid receptor interactions and metabolic pathways in preclinical research.

Basic Information

Item	Details
Product Name	(8α)-14β-Hydroxy-3-Methoxy-D-Homoestra-1,3,5(10),9(11)-Tetren-17A-One
CAS No.	17908-44-0
Molecular Formula	C20H26O3
Molecular Weight	314.42 g/mol
Synonyms	14β-Hydroxy-3-methoxy-D-homoestra-1,3,5(10),9(11)-tetraen-17a-one; 14β-Hydroxy-3-methoxy-D-homoestra-1,3,5(10),9(11)-tetraen-17-one (D-homo form); 8α-Estra-1,3,5(10),9(11)-tetraene-14β-ol-3-methoxy-17a-one; 14β-Hydroxy-3-methoxyestra-1,3,5(10),9(11)-tetraen-17a-one (D-homo); A modified estrane derivative.
EINECS	Contact for details

Quality Control

Our (8α)-14β-Hydroxy-3-Methoxy-D-Homoestra-1,3,5(10),9(11)-Tetren-17A-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.