Description

(R)-3,5-Dihydroxy-3-Methylvaleric Acid is a high-purity chiral intermediate and building block of significant importance in advanced organic synthesis. This compound matters for its role as a key precursor in the production of statin-class pharmaceuticals and other fine chemicals requiring specific stereochemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and specialty chemical industries for developing new active pharmaceutical ingredients (APIs) and complex molecules.

Application

• Pharmaceutical Intermediate: Critical chiral building block for the synthesis of HMG-CoA reductase inhibitors (statins) and other therapeutic agents.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and metabolic pathway research.
• Asymmetric Synthesis: Serves as a starting material for the preparation of complex, stereochemically defined molecules in medicinal chemistry.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-3,5-Dihydroxy-3-Methylvaleric Acid
CAS No.	17817-88-8
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	(R)-3,5-Dihydroxy-3-methylpentanoic acid; (3R)-3,5-Dihydroxy-3-methylpentanoic acid; (R)-3-Methylmevalonic acid; D-3,5-Dihydroxy-3-methylvaleric acid; (R)-Mevalonic acid lactone precursor; (R)-HMG acid; (R)-3-Hydroxy-3-methylglutaryl acid (reduced form); (3R)-3-Methyl-3,5-dihydroxypentanoic acid
EINECS	Contact for details

Quality Control

Our (R)-3,5-Dihydroxy-3-Methylvaleric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.