Description

Aescigenin is a bioactive triterpenoid saponin aglycone derived from the horse chestnut tree (*Aesculus hippocastanum*). This compound serves as a crucial reference standard and active pharmaceutical ingredient (API) for research and development in the pharmaceutical and nutraceutical industries. It is primarily sought by manufacturers and research institutions focused on vascular health, anti-inflammatory, and antioxidant applications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of aescin-containing products in quality control laboratories.
• Active Pharmaceutical Ingredient (API): Serves as a key intermediate or active component in the formulation of venotonic and anti-inflammatory drugs.
• Nutraceutical Research: Investigated for its potential benefits in dietary supplements targeting circulatory support and capillary health.
• Cosmeceutical Formulations: Incorporated into topical creams and serums for its purported anti-edema and skin-protective properties.
• Biochemical Research: Utilized in *in vitro* and *in vivo* studies to elucidate mechanisms of action related to inflammation and vascular permeability.
• Veterinary Medicine: Applied in formulations for animal health, particularly for conditions involving inflammation and swelling.

Basic Information

Product Name	Aescigenin
CAS No.	17806-68-7
Molecular Formula	C55H86O24
Molecular Weight	1131.26 g/mol
Synonyms	Aescinogenin; Escigenin; β-Aescin; Escin; Aesculus saponin; Aescin (aglycone); (3β,16α,21β,22α)-21,22-Diacetoxy-16,28-dihydroxyolean-12-en-3-yl β-D-glucopyranosiduronic acid
EINECS	Contact for details

Quality Control

Our Aescigenin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Conforms to reference retention time
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.