Description

Phenyl Trifluoromethanesulfonate is a versatile and highly reactive triflate ester, widely recognized as a superior electrophile and phenylating agent in advanced organic synthesis. Its value lies in its exceptional leaving group ability, enabling efficient C-C and C-heteroatom bond formation under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for constructing complex molecules and developing novel materials.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the phenyl group in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Manufacturing: Used in the production of advanced pesticides, herbicides, and fungicides where phenyl moieties are required.
• Cross-Coupling Reactions: Serves as an effective electrophilic partner in Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions.
• Polymer & Material Science: Employed as a monomer or functionalization agent in the development of specialty polymers and advanced materials.
• Ligand & Catalyst Preparation: Utilized for the synthesis of organometallic complexes and specialized ligands used in catalysis.
• Laboratory Research & Process Development: A critical tool in academic and industrial R&D for method development and scale-up studies.

Basic Information

Product Name	Phenyl Trifluoromethanesulfonate
CAS No.	17763-67-6
Molecular Formula	C7H5F3O3S
Molecular Weight	226.17 g/mol
Synonyms	Phenyl Triflate; Trifluoromethanesulfonic Acid Phenyl Ester; Phenyl Trifluoromethanesulphonate; Phenyl Triflyl Ester; Phenyl Perfluoroethanesulfonate (historical); Benzenol, Trifluoromethanesulfonate; Phenyl Ester of Trifluoromethanesulfonic Acid
EINECS	Contact for details

Quality Control

Our Phenyl Trifluoromethanesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including purity by GC/HPLC, identity confirmation by NMR and IR spectroscopy, and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality system is designed to support cGMP and ISO standards for demanding industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are kept tightly sealed and away from heat, sparks, and open flame. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.4 g/mL
Refractive Index (n20D)	~1.38

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.