Description

10H-Phenoxazine-1-Carboxylic Acid, 8-(Trifluoromethyl)- is a specialized trifluoromethyl-substituted phenoxazine derivative that serves as a high-value synthetic intermediate. Its unique structure, featuring both a carboxylic acid group and an electron-withdrawing trifluoromethyl moiety, makes it a critical building block for advanced material and pharmaceutical research. This compound is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and organic electronics sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Agrochemical Research: Used to develop new herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a core component for electron-transport materials or host materials in emissive layers due to the phenoxazine scaffold's electronic properties.
• Dye and Pigment Synthesis: Serves as a starting material for creating specialized dyes with unique colorfastness and fluorescence properties.
• Ligand for Catalysis: Can be utilized to develop novel ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Academic & Industrial R&D: A valuable tool compound for exploring new chemical spaces and reaction methodologies in synthetic chemistry laboratories.

Basic Information

Product Name	10H-Phenoxazine-1-Carboxylic Acid, 8-(Trifluoromethyl)-
CAS No.	17710-79-1
Molecular Formula	C14H8F3NO3
Molecular Weight	295.22 g/mol
Synonyms	8-(Trifluoromethyl)-10H-phenoxazine-1-carboxylic acid; 1-Carboxy-8-trifluoromethylphenoxazine; 8-Trifluoromethylphenoxazine-1-carboxylic Acid; 10H-Phenoxazine-1-carboxylic acid, 8-(trifluoromethyl)-; 17710-79-1; 8-CF3-Phenoxazine-1-carboxylic acid; 1-Phenoxazinecarboxylic acid, 8-(trifluoromethyl)-10H-
EINECS	Contact for details

Quality Control

Every batch of 10H-Phenoxazine-1-Carboxylic Acid, 8-(Trifluoromethyl)- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR and NMR), and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.