Description

Dimethyl (1R,6R)-Cyclohex-3-Ene-1,6-Dicarboxylate is a high-purity chiral diester building block of significant synthetic utility. Its defined stereochemistry and functional group array make it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought by pharmaceutical and fine chemical research organizations for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Asymmetric Synthesis: Used in stereoselective reactions to introduce the (1R,6R) cyclohexene scaffold into target molecules.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and chemical biology research.
• Polymer Chemistry: Potential monomer for creating novel polymers with specific stereochemical properties.

Basic Information

Product Name	Dimethyl (1R,6R)-Cyclohex-3-Ene-1,6-Dicarboxylate
CAS No.	17673-68-6
Molecular Formula	C10H14O4
Molecular Weight	198.22 g/mol
Synonyms	(1R,6R)-Cyclohex-3-ene-1,6-dicarboxylic acid dimethyl ester; (1R,6R)-Dimethyl cyclohex-3-ene-1,6-dicarboxylate; (-)-Dimethyl (1R,6R)-cyclohex-3-ene-1,6-dicarboxylate; (1R,6R)-1,6-Dimethoxycarbonyl-3-cyclohexene; (1R,6R)-3-Cyclohexene-1,6-dicarboxylic acid dimethyl ester; Dimethyl (1R,6R)-1,2,3,6-tetrahydrophthalate; (1R,6R)-Tetrahydrophthalic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl (1R,6R)-Cyclohex-3-Ene-1,6-Dicarboxylate is produced under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet stringent specifications. Certificates of Analysis (COA) detailing assay, chiral purity (by chiral HPLC or GC), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.