Description

Methyl 2-Bromo-2-Butenoate is a versatile brominated ester building block, primarily valued for its role as a key intermediate in organic synthesis. Its reactive α,β-unsaturated carbonyl structure, activated by the bromine substituent, makes it a crucial reagent for introducing functionalized butenoate moieties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring functionalized olefinic or ester components.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactivity to create novel bioactive compounds.
• Organic Synthesis Building Block: Employed in Michael additions, cross-coupling reactions (e.g., Suzuki, Heck), and nucleophilic substitution reactions to construct complex organic molecules.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialized polymers and advanced materials.
• Flavor and Fragrance Industry: Utilized as a precursor for synthesizing specific ester-based aroma chemicals.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	Methyl 2-Bromo-2-Butenoate
CAS No.	17642-18-1
Molecular Formula	C5H7BrO2
Molecular Weight	179.01 g/mol
Synonyms	2-Bromo-2-butenoic acid methyl ester; Methyl α-bromocrotonate; Methyl (E)-2-bromo-2-butenoate; 2-Bromobut-2-enoic acid methyl ester; Methyl 2-bromocrotonate; Crotonic acid, 2-bromo-, methyl ester; Methyl trans-2-bromo-2-butenoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-2-Butenoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 2°C and 8°C for extended stability, although short-term storage at 15-25°C is acceptable. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.45 - 1.55
Refractive Index (20°C)	1.480 - 1.490

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.