Description

Acetimidothioic Acid Methyl Ester is a versatile sulfur-containing organic building block with significant synthetic utility. Its unique structure, featuring both an imidothioate and an ester group, makes it a valuable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working in fine chemical synthesis. Its application spans the development of novel heterocycles, ligands, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiazole, imidazole, and other nitrogen-sulfur heterocycles commonly found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific sulfur-nitrogen motifs for bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs where the thioester functionality is crucial for mimicking natural structures.
• Chemical Biology Probes: Useful in the development of activity-based probes and other tools for studying enzymatic mechanisms and protein interactions.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique electronic or adhesive properties.

Basic Information

Product Name	Acetimidothioic Acid Methyl Ester
CAS No.	17572-18-8
Molecular Formula	C3H7NOS
Molecular Weight	105.16 g/mol
Synonyms	Methyl acetimidothioate; Acetimidothioic acid methyl ester; Methyl thioacetimidate; Methanethioic acid, 1-imino-, methyl ester; N-Methylthioacetimidate; Acetothioic acid, imino-, methyl ester; Methyl acetimidothioate; Methyl N-thioacetimidate
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard grade for Acetimidothioic Acid Methyl Ester typically meets a purity specification of ≥95% (by HPLC/NMR), suitable for most synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment. We can also support custom synthesis projects with tailored purity grades and analytical specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability. Allow the container to reach ambient temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.