Description

(Tetrahydro-Pyran-2-Yloxy)-Acetonitrile is a versatile organic nitrile building block characterized by its tetrahydropyranyl-protected oxyacetonitrile structure. This compound is valued for its role as a key synthetic intermediate, enabling the controlled introduction of functional groups in complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and custom synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing heterocyclic compounds and nucleoside analogs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive nitrile group.
• Fine Chemical Production: Serves as a specialized precursor for dyes, pigments, and advanced materials requiring specific ether-linked nitrile functionalities.
• Academic & Industrial Research: Employed in methodological studies and as a starting material for developing new synthetic routes and catalysts.
• Peptide Mimetics & Bioconjugation: The protected hydroxyl group makes it useful for creating linkers and modified amino acid derivatives in bioconjugate chemistry.

Basic Information

Item	Detail
Product Name	(Tetrahydro-Pyran-2-Yloxy)-Acetonitrile
CAS No.	17521-49-2
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	2-(Tetrahydro-2H-pyran-2-yloxy)acetonitrile; THP-O-Acetonitrile; (THPO)Acetonitrile; 2-(Oxan-2-yloxy)acetonitrile; Acetonitrile, [(tetrahydro-2H-pyran-2-yl)oxy]-; (2-Oxanyloxy)acetonitrile; O-(Tetrahydro-2H-pyran-2-yl)glycolonitrile
EINECS	Contact for details

Quality Control

Our (Tetrahydro-Pyran-2-Yloxy)-Acetonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.