Description

5-Fluoroacenaphthylene is a fluorinated polycyclic aromatic hydrocarbon (PAH) derivative, serving as a critical advanced intermediate in synthetic organic chemistry. Its value lies in its unique structural framework, which combines the planar, conjugated system of acenaphthylene with the electronic and steric influence of a fluorine substituent, enabling precise modifications to molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) research, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom to improve pesticidal activity and environmental persistence.
• Organic Electronic Materials: Serves as a precursor for developing organic semiconductors, light-emitting diodes (OLEDs), and photovoltaic materials due to its conjugated π-system.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalysis, influencing reaction selectivity and efficiency.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on aromatic systems.
• Polymer Science: Can be incorporated as a monomer or additive to impart specific thermal, optical, or electronic properties to high-performance polymers.

Basic Information

Product Name	5-Fluoroacenaphthylene
CAS No.	17521-01-6
Molecular Formula	C₁₂H₇F
Molecular Weight	170.19 g/mol
Synonyms	5-Fluoroacenaphthylene; 1-Fluoroacenaphthylene; Acenaphthylene, 5-fluoro-; 5-Fluoro-1H-cyclopenta[l]phenanthrene; 5-Fluoro-1,2-dihydroacenaphthylene; 5-Fluoro-1,2-dihydrocyclopenta[de]naphthalene; 5-Fluoroaceanthrylene (common misnomer); 5-Fluoro-aceanthrene
EINECS	Contact for details

Quality Control

Our 5-Fluoroacenaphthylene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.