Description

5-(Trifluoromethyl)-2-Furaldehyde is a high-value fluorinated heterocyclic building block with the CAS registry number 17515-80-9. This compound is prized for its unique trifluoromethyl group, which imparts enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with improved properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Fluorine Chemistry Building Block: A versatile starting material for introducing the CF3 moiety into more complex molecular architectures in discovery chemistry.

Basic Information

Product Name	5-(Trifluoromethyl)-2-Furaldehyde
CAS No.	17515-80-9
Molecular Formula	C6H3F3O2
Molecular Weight	164.08 g/mol
Synonyms	5-(Trifluoromethyl)furfural; 2-Formyl-5-(trifluoromethyl)furan; 5-Trifluoromethyl-2-furaldehyde; 5-Trifluoromethylfurfural; α,α,α-Trifluoro-5-furaldehyde; 2-Furaldehyde, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-furancarboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-2-Furaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and highly volatile nature, containers must be kept tightly sealed and away from heat and ignition sources. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.