Description

Methyl 4-Hydroxycyclohexanecarboxylate CAS NO 17449-76-2 is a versatile cyclohexane derivative that serves as a crucial chiral building block and intermediate in advanced organic synthesis. Its value lies in the combination of a carboxylate ester and a hydroxyl group on the cyclohexane ring, enabling diverse chemical transformations. This compound is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators with specific stereochemistry.
• Liquid Crystal Materials: Intermediate in the production of cyclohexane-based components for liquid crystal displays (LCDs).
• Polymer Chemistry: Monomer or co-monomer for specialty polyesters and polycarbonates with modified thermal and mechanical properties.
• Fragrance & Flavor Chemistry: Intermediate for synthesizing musk and other complex aroma chemicals.
• Organic Synthesis Reagent: Used in asymmetric synthesis, hydrogenation studies, and as a precursor for other functionalized cyclohexanes.

Basic Information

Product Name	Methyl 4-Hydroxycyclohexanecarboxylate
CAS No.	17449-76-2
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	4-Hydroxycyclohexanecarboxylic Acid Methyl Ester; Methyl 4-Hydroxycyclohexanecarboxylate; Methyl trans-4-Hydroxycyclohexanecarboxylate; Methyl cis-4-Hydroxycyclohexanecarboxylate; 4-Hydroxy-cyclohexanecarboxylic acid methyl ester; Cyclohexanecarboxylic acid, 4-hydroxy-, methyl ester; Methyl 4-hydroxycyclohexanecarboxylate (cis- and trans- mixture)
EINECS	Contact for details

Quality Control

Our Methyl 4-Hydroxycyclohexanecarboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (typical 98-99%)
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.