Description

L-Proline, 1-Nitroso-, Ethyl Ester (9Ci) is a specialized nitroso derivative of the amino acid proline, serving as a valuable synthetic intermediate in advanced organic chemistry. This compound is particularly significant for its role in constructing complex molecular architectures and introducing functional groups under controlled conditions. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry, process development, and novel material synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring proline-based scaffolds.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its reactive nitroso group.
• Peptide Chemistry: Acts as a modified proline residue for the study of peptide conformation and stability, or for creating structurally unique peptides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological processes and protein interactions.
• Academic & Industrial R&D: Serves as a versatile reagent in methodological development and exploratory synthesis within organic chemistry laboratories.
• Fine Chemical Synthesis: Utilized in the multi-step production of complex, high-value specialty chemicals and advanced materials.

Basic Information

Product Name	L-Proline, 1-Nitroso-, Ethyl Ester (9Ci)
CAS No.	17431-20-8
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	Ethyl 1-Nitroso-L-prolinate; L-Proline, 1-nitroso-, ethyl ester; 1-Nitroso-L-proline ethyl ester; Ethyl (S)-1-nitroso-2-pyrrolidinecarboxylate; 2-Pyrrolidinecarboxylic acid, 1-nitroso-, ethyl ester, (S)-; (S)-Ethyl 1-nitroso-2-pyrrolidinecarboxylate; 1-Nitroso-L-proline ethyl ester; Ethyl 1-nitroso-L-prolinate
EINECS	Contact for details

Quality Control

Our L-Proline, 1-Nitroso-, Ethyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Chiral Purity	≥ 98% ee
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.