Description

(S)-(+)-2-Hydroxy-3-Methylbutyric Acid CAS NO 17407-55-5 is a high-purity, single-enantiomer chiral building block essential for asymmetric synthesis. This compound is valued for its role in constructing complex molecular architectures with precise stereochemical control. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, antibiotics, and other active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy.
• Fine Chemical Production: Serves as a versatile building block for flavors, fragrances, and specialty chemicals where optical purity is paramount.
• Biochemical Research: Employed in enzymatic studies and as a precursor for synthesizing modified amino acids and peptides.
• Catalyst & Ligand Development: Useful in the preparation of chiral catalysts and ligands for asymmetric hydrogenation and other catalytic transformations.
• Nutritional Supplements: Potential intermediate in the synthesis of certain bioactive compounds and metabolites for nutritional science.

Basic Information

Product Name	(S)-(+)-2-Hydroxy-3-Methylbutyric Acid
CAS No.	17407-55-5
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(S)-2-Hydroxy-3-methylbutanoic acid; (S)-(+)-2-Hydroxyisovaleric acid; L-2-Hydroxy-3-methylbutyric acid; (S)-HMB; (2S)-2-Hydroxy-3-methylbutanoic acid; (S)-2-Hydroxy-3-methylbutyric acid; (S)-α-Hydroxyisovaleric acid
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Hydroxy-3-Methylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for enantiomeric excess and chemical purity. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	82 - 86 °C
Specific Rotation [α]20/D	+14.0° to +16.0° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.