Description

(-)-1,4-Di-o-Benzyl-L-Threitol CAS NO 17401-06-8 is a high-purity, enantiomerically pure chiral building block and ligand. This compound is valued for its role in asymmetric synthesis, serving as a crucial precursor and auxiliary in the preparation of complex pharmaceutical intermediates and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and catalysts.

Application

• Asymmetric Synthesis: A key chiral auxiliary and ligand for transition metal-catalyzed reactions, including asymmetric hydrogenations and oxidations.
• Pharmaceutical Intermediates: Critical precursor in the synthesis of chiral drugs, particularly those targeting cardiovascular and central nervous system diseases.
• Catalyst Development: Used in the design and preparation of novel chiral catalysts for enantioselective transformations.
• Agrochemicals: Building block for the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer or modifier for creating chiral polymers and liquid crystals with specific optical properties.
• Academic & Industrial Research: A standard reagent for methodological development in organic chemistry and process chemistry laboratories.

Basic Information

Product Name	(-)-1,4-Di-o-Benzyl-L-Threitol
CAS No.	17401-06-8
Molecular Formula	C18H22O4
Molecular Weight	302.36 g/mol
Synonyms	(2R,3S)-1,4-Bis(benzyloxy)butane-2,3-diol; L-Threitol 1,4-Dibenzylester; (-)-1,4-Di-O-benzyl-L-threitol; 1,4-Di-O-benzyl-L-threitol; (2S,3S)-1,4-Dibenzyloxy-2,3-butanediol (enantiomer); DIBENZYL L-THREITOL; 1,4-Di-O-benzylthreitol
EINECS	Contact for details

Quality Control

Our (-)-1,4-Di-o-Benzyl-L-Threitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.