Description

3-Acetyl-Indole-5-Carbonitrile is a high-purity, versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both acetyl and nitrile functional groups, makes it an invaluable intermediate for constructing complex heterocyclic compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Material Science: Serves as a monomer or functional unit in the creation of advanced polymers, organic semiconductors, and light-emitting materials.
• Chemical Synthesis: Employed as a versatile scaffold for further functionalization, including ring closure reactions and the introduction of complex side chains.
• Biochemical Research: Utilized as a probe or inhibitor in enzymatic studies and biochemical pathway analysis.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized indole-based dyes and colorants.

Basic Information

Product Name	3-Acetyl-Indole-5-Carbonitrile
CAS No.	17380-19-7
Molecular Formula	C11H8N2O
Molecular Weight	184.20 g/mol
Synonyms	1-(5-Cyano-1H-indol-3-yl)ethanone; 3-Acetyl-5-cyanoindole; 5-Cyano-3-acetylindole; 3-Acetyl-1H-indole-5-carbonitrile; 1H-Indole-5-carbonitrile, 3-acetyl-; Ethanone, 1-(5-cyano-1H-indol-3-yl)-; 3-Acetylindole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Acetyl-Indole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures a reliable supply of high-quality material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.