Description

(2-Iodoethyl)Benzene CAS NO 17376-04-4 is a versatile organoiodine compound featuring a reactive iodoethyl side chain attached to a benzene ring. This structure makes it a valuable alkylating agent and key synthetic intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring phenethylamine or aryl-ethyl motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the introduction of an iodinated ethylbenzene group is required.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of liquid crystals, organic semiconductors, and other advanced organic materials.
• Organic Synthesis Reagent: Functions as an efficient alkylating agent in nucleophilic substitution reactions to introduce the 2-phenylethyl group.
• Radiolabeling Precursor: Can be utilized as a starting material for the synthesis of iodine-123 or iodine-131 labeled compounds for medical imaging and research.

Basic Information

Product Name	(2-Iodoethyl)Benzene
CAS No.	17376-04-4
Molecular Formula	C8H9I
Molecular Weight	232.06 g/mol
Synonyms	2-Phenylethyl iodide; (2-Iodoethyl)benzene; β-Iodoethylbenzene; 1-Iodo-2-phenylethane; Phenethyl iodide; Benzene, (2-iodoethyl)-; 2-Iodoethylbenzene; (β-Iodoethyl)benzene
EINECS	241-408-9

Quality Control

Our (2-Iodoethyl)Benzene is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque. For long-term storage, consider under an inert atmosphere such as nitrogen or argon to maximize stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Specific Gravity (20°C)	1.50 - 1.55
Refractive Index (n20D)	1.580 - 1.590

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.