Description

Salicylic Acid 4-Nitrophenyl Ester is a specialized organic chemical ester derived from salicylic acid and 4-nitrophenol. This compound serves as a critical chromogenic substrate and synthetic intermediate in biochemical research and fine chemical synthesis. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic reagent manufacturers, and academic research institutions for enzyme activity studies and the development of analytical methods.

Application

• Enzyme Substrate: Widely used as a chromogenic substrate for detecting and quantifying the activity of esterases, lipases, and other hydrolytic enzymes in biochemical assays.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex active pharmaceutical ingredients (APIs) and prodrugs.
• Diagnostic Reagents: Incorporated into kits and reagents for clinical diagnostics and life science research to measure enzymatic processes.
• Biochemical Research: Employed in mechanistic studies of enzyme kinetics and inhibition, providing a colorimetric readout upon hydrolysis.
• Chemical Synthesis: Acts as a protected or activated form of salicylic acid for selective organic synthesis reactions in fine chemical production.

Basic Information

Product Name	Salicylic Acid 4-Nitrophenyl Ester
CAS No.	17374-48-0
Molecular Formula	C13H9NO5
Molecular Weight	259.21 g/mol
Synonyms	4-Nitrophenyl salicylate; p-Nitrophenyl salicylate; Salicylic acid p-nitrophenyl ester; 2-Hydroxybenzoic acid 4-nitrophenyl ester; PNPS; NSC 403914; 4-Nitrophenyl 2-hydroxybenzoate
EINECS	Contact for details

Quality Control

Our Salicylic Acid 4-Nitrophenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.