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Cbz-Neuraminic Acid CAS NO 17367-66-7


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CAS No.:17367-66-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Cbz-Neuraminic Acid CAS NO 17367-66-7 is a protected derivative of neuraminic acid, a fundamental nine-carbon monosaccharide and the parent structure of sialic acids. This compound is a critical synthetic intermediate and biochemical tool for the study of sialobiology, enabling the controlled introduction of sialic acid motifs. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for glycosylation studies, glycoconjugate synthesis, and the development of carbohydrate-based therapeutics and vaccines.

Application

  • Glycoconjugate Synthesis: A key building block for the chemical and enzymatic synthesis of sialylated oligosaccharides, glycopeptides, and glycolipids.
  • Pharmaceutical Intermediates: Serves as a crucial precursor in the research and development of sialic acid-based drugs, including antiviral agents and anti-inflammatory compounds.
  • Biochemical Research: Used as a standard and substrate in enzymatic assays to study sialidases (neuraminidases) and sialyltransferases.
  • Vaccine Development: Employed in the design and production of conjugate vaccines where sialic acid antigens are targeted.
  • Diagnostic Reagent Manufacturing: Utilized in the production of reagents for detecting sialic acid levels, which can be biomarkers for certain diseases.
  • Glycoengineering: A vital tool for the chemoenzymatic remodeling of cell surface glycans to study cell-cell interactions and signaling.

Basic Information

Product Name Cbz-Neuraminic Acid
CAS No. 17367-66-7
Molecular Formula C₁₇H₂₃NO₉
Molecular Weight 385.37 g/mol
Synonyms 5-Acetamido-2-[(benzyloxy)carbonyl]amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid; N-Carbobenzoxy-neuraminic acid; N-Cbz-neuraminic acid; Nα-Cbz-Neu5Ac; Benzyl N-(5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosyl)carbamate
EINECS Contact for details

Quality Control

Our Cbz-Neuraminic Acid is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high purity and consistency, with specifications aligned with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with every shipment to support your R&D and cGMP documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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