Description

Acetic Acid, 2,2,2-Trifluoro-, 2-Methylpropyl Ester is a specialized fluorinated organic ester, also known by its CAS number 17355-83-8. This compound is valued for its unique combination of being a highly volatile and strong acid/organic solvent, making it a critical intermediate and reagent in advanced chemical synthesis. It is primarily sought by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring precise fluorination and esterification chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Specialty Polymer & Resin Modifier: Serves as a monomer or modifying agent to impart specific properties like chemical resistance or altered surface energy in high-performance polymers.
• Organic Synthesis Reagent: Employed as a versatile reagent in academic and industrial research for esterification, transesterification, and as a source of the trifluoroacetyl group.
• Electrolyte Additive: Investigated for use in advanced battery formulations to improve electrolyte stability and performance at extreme voltages.
• Surface Treatment & Coatings: Utilized in formulations for specialty coatings that require specific wetting, adhesion, or release properties.

Basic Information

Product Name	Acetic Acid, 2,2,2-Trifluoro-, 2-Methylpropyl Ester
CAS No.	17355-83-8
Molecular Formula	C7H11F3O2
Molecular Weight	184.16 g/mol
Synonyms	Isobutyl 2,2,2-Trifluoroacetate; 2-Methylpropyl 2,2,2-Trifluoroacetate; 2,2,2-Trifluoroacetic Acid Isobutyl Ester; Trifluoroacetic Acid Isobutyl Ester; TFA Isobutyl Ester; Isobutyl Trifluoroacetate; 17355-83-8; NSC 22198
EINECS	Contact for details

Quality Control

Our Acetic Acid, 2,2,2-Trifluoro-, 2-Methylpropyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.355 - 1.365
Density (20°C)	1.15 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.