Description

Benzo[B]Thiophene-4-Carbonitrile is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its rigid, fused-ring structure and the reactive nitrile functional group, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, serving as a critical intermediate for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor or core structure in the synthesis of electron-transport materials and emissive layer components for display and lighting technologies.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis and organocatalysts due to its electron-deficient aromatic system.
• Polymer and Material Science: Acts as a monomer or functional additive for creating specialty polymers with enhanced thermal stability or specific electronic properties.
• Chemical Research & Development: A valuable reagent for method development, library synthesis, and exploring new chemical spaces in academic and industrial R&D settings.

Basic Information

Product Name	Benzo[B]Thiophene-4-Carbonitrile
CAS No.	17347-34-1
Molecular Formula	C9H5NS
Molecular Weight	159.21 g/mol
Synonyms	4-Cyanobenzo[b]thiophene; Benzo[b]thiophene-4-carbonitrile; 4-Benzo[b]thienylcarbonitrile; 1-Benzothiophene-4-carbonitrile; 4-Cyano-1-benzothiophene; NSC 221986; 4-CN-BT
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-4-Carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles verified by HPLC, GC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.