Description

2,2,2-Trichloroethyl Chloroformate is a specialized organic reagent primarily used as a versatile protecting group agent and an intermediate in fine chemical synthesis. Its high reactivity makes it a critical component for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the life sciences, advanced materials, and specialty chemical sectors who require precise and reliable building blocks for their processes.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protecting groups for amines and alcohols.
• Peptide Synthesis: Used as a coupling agent and for the protection of functional groups during solid-phase and solution-phase peptide synthesis.
• Agrochemical Production: Serves as a precursor in the manufacture of herbicides, fungicides, and other crop protection agents.
• Polymer Chemistry: Employed in the production of specialty polymers and as a modifier for polymer chains to impart specific properties.
• Organic Synthesis Reagent: Acts as a chloroformylating agent for the preparation of carbonates, carbamates, and other carbonyl derivatives in research and development.
• Chemical Derivatization: Utilized in analytical chemistry for the derivatization of compounds to enhance detection or separation in techniques like GC-MS or HPLC.

Basic Information

Product Name	2,2,2-Trichloroethyl Chloroformate
CAS No.	17341-93-4
Molecular Formula	C3H2Cl4O2
Molecular Weight	211.86 g/mol
Synonyms	Trichloroethyl Chloroformate; 2,2,2-Trichloroethyl Carbonochloridate; Chloroformic Acid 2,2,2-Trichloroethyl Ester; Troc-Cl; Troc Chloride; 2,2,2-Trichloroethoxycarbonyl Chloride; Trichloroethyloxycarbonyl Chloride; Carbonochloridic Acid, 2,2,2-Trichloroethyl Ester
EINECS	241-379-6

Quality Control

Our 2,2,2-Trichloroethyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC or HPLC, identity confirmation (IR), and impurity profiling, to ensure it meets high-purity standards suitable for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maintain stability and minimize volatility. Due to its moisture-sensitive and highly volatile nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.55 - 1.60 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.