Description

1,2-Dibromo-3,4,5-Trifluorobenzene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the precise introduction of bromine and fluorine substituents into complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display and lighting materials, improving performance and durability.
• Polymer Modification: Employed to introduce halogenated phenyl groups into polymer backbones, altering thermal and chemical resistance properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and constructing diverse chemical libraries.

Basic Information

Product Name	1,2-Dibromo-3,4,5-Trifluorobenzene
CAS No.	17299-94-4
Molecular Formula	C6HBr2F3
Molecular Weight	291.87 g/mol
Synonyms	1,2-Dibromo-3,4,5-trifluorobenzene; 3,4,5-Trifluoro-1,2-dibromobenzene; Benzene, 1,2-dibromo-3,4,5-trifluoro-; 1,2-Dibromotrifluorobenzene; NSC 172999
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-3,4,5-Trifluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	45 - 50 °C
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.