Description

(S)-2-(((4-Amino-1-Carboxy-4-Oxobutyl)Amino)Carbonyl)Benzoic Acid is a high-purity, non-proteinogenic amino acid derivative with a defined stereochemistry. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting specific biological pathways. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical sectors who require high-fidelity intermediates for the production of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially for protease inhibitors and other targeted therapies.
• Peptidomimetic Research: Used in the design and construction of peptide analogs and mimetics to enhance stability, bioavailability, and receptor selectivity.
• Bioconjugation & Probe Development: Serves as a specialized linker or functional handle for creating labeled compounds used in biochemical assays and diagnostic research.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Chemical Biology Tool: Utilized to study enzyme mechanisms or protein-protein interactions where a specific, unnatural amino acid motif is required.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-2-(((4-Amino-1-Carboxy-4-Oxobutyl)Amino)Carbonyl)Benzoic Acid
CAS No.	17283-87-3
Molecular Formula	C13H14N2O7
Molecular Weight	310.26 g/mol
Synonyms	N-(4-Amino-1,4-dicarboxybutyl)phthalamic acid; (S)-2-[[(4-Amino-1-carboxy-4-oxobutyl)amino]carbonyl]benzoic acid; L-2-[[(4-Amino-1-carboxy-4-oxobutyl)amino]carbonyl]benzoic acid; Phthaloyl-L-glutamic acid monoamide; A key intermediate for Glufosfamide synthesis; L-α-Phthalimidoglutaramic acid; 2-[(1-Carboxy-4-amino-4-oxobutyl)carbamoyl]benzoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-(((4-Amino-1-Carboxy-4-Oxobutyl)Amino)Carbonyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.