Description

Isocucurbitacin B CAS NO 17278-28-3 is a specialized cucurbitacin derivative, a class of highly oxygenated tetracyclic triterpenoids known for their potent bioactivity. This compound is of significant interest for its role as a key intermediate and reference standard in advanced pharmaceutical and biochemical research. It is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of high-purity fine chemicals focused on oncology, inflammation, and metabolic disorder studies.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification, purity assessment, and quantification of cucurbitacin analogs in drug development and quality control laboratories.
• Biochemical Research Reagent: Used in in vitro and in vivo studies to investigate mechanisms of action related to anti-cancer, anti-inflammatory, and hepatoprotective activities.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and development of novel therapeutic agents targeting specific cellular pathways.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the standardization and authentication of plant extracts from the Cucurbitaceae family.
• Academic & Contract Research: Essential for university and CRO laboratories conducting fundamental research on triterpenoid chemistry and pharmacology.

Basic Information

Product Name	Isocucurbitacin B
CAS No.	17278-28-3
Molecular Formula	C32H46O8
Molecular Weight	558.71 g/mol
Synonyms	Isocucurbitacin B; 23,24-Dihydroisocucurbitacin B; (23S)-23,24-Dihydroisocucurbitacin B; 3β,16α,20(R),25-Tetrahydroxy-10α-cucurbita-5,23-diene-11,22-dione; Cucurbitacin derivative; Triterpenoid glycoside aglycone
EINECS	Contact for details

Quality Control

Our Isocucurbitacin B is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR, MS), and residual solvent analysis to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.