Description

2-(4-Methylphenyl)-1,3-Thiazole-4-Carboxylic Acid is a high-purity organic building block and key heterocyclic intermediate of significant commercial importance. Its value lies in its versatile molecular scaffold, which is integral to the synthesis of advanced pharmaceuticals, agrochemicals, and functional materials. This compound is primarily needed by research institutions and industrial manufacturers in the life sciences and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photoactive materials due to its electron-rich thiazole core.
• Biochemical Probe Development: Employed in medicinal chemistry to create molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	2-(4-Methylphenyl)-1,3-Thiazole-4-Carboxylic Acid
CAS No.	17228-99-8
Molecular Formula	C11H9NO2S
Molecular Weight	219.26 g/mol
Synonyms	4-(4-Methylphenyl)-1,3-thiazole-2-carboxylic acid; p-Tolyl-1,3-thiazole-4-carboxylic acid; 2-(p-Tolyl)-4-thiazolecarboxylic acid; 4-Carboxy-2-(4-methylphenyl)thiazole; 2-(4-Methylphenyl)-4-thiazolecarboxylic acid; 17228-99-8; 4-Thiazolecarboxylic acid, 2-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our production of 2-(4-Methylphenyl)-1,3-Thiazole-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthesis workflows. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity profiles and impurity characterization. Our quality systems are designed to support applications requiring high-purity intermediates under cGMP and ISO 9001 frameworks where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.