Description

4-Cyanobenzylbromide is a versatile and highly reactive organic bromide intermediate, essential for constructing complex molecular architectures. Its value lies in the dual functionality of the benzyl bromide and nitrile groups, enabling efficient carbon-carbon bond formation and further functional group transformations. This compound is a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for synthesizing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug molecules, including kinase inhibitors and other biologically active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating specialized organic electronic materials.
• Polymer & Resin Modification: Employed to introduce cyanobenzyl functional groups into polymer chains to alter physical properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings.
• Organic Synthesis & Research: Fundamental reagent for nucleophilic substitution reactions and the preparation of more complex cyanobenzyl derivatives in R&D laboratories.

Basic Information

Product Name	4-Cyanobenzylbromide
CAS No.	17201-41-3
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	α-Bromo-4-cyanotoluene; p-Cyanobenzyl Bromide; 4-(Bromomethyl)benzonitrile; (4-Cyanophenyl)methyl Bromide; 1-(Bromomethyl)-4-cyanobenzene; p-Cyanobenzylbromide; 4-Cyanobenzyl Bromide; p-Cyanobenzyl Bromide
EINECS	Contact for details

Quality Control

Our 4-Cyanobenzylbromide is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be kept separate from strong acids and incompatible materials. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.