Description

4α-tert-Butylcyclohexane-1α-Carboxylic Acid Methyl Ester is a high-purity, synthetically valuable cyclohexane derivative. This compound serves as a crucial chiral intermediate and building block in advanced organic synthesis, offering a rigid, sterically defined structure. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fragrance industries for the production of complex target molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a conformationally locked cyclohexyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its structural properties can influence biological activity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, ligands, and catalysts for asymmetric synthesis.
• Fragrance & Flavor Chemistry: Potential intermediate for creating synthetic musks and other complex aroma chemicals due to its stable, bulky terpene-like structure.
• Material Science Research: Employed in the development of novel polymers or liquid crystals where the tert-butylcyclohexane unit can impart specific physical properties.

Basic Information

Product Name	4α-tert-Butylcyclohexane-1α-Carboxylic Acid Methyl Ester
CAS No.	17177-76-3
Molecular Formula	C₁₂H₂₂O₂
Molecular Weight	198.30 g/mol
Synonyms	trans-4-tert-Butylcyclohexanecarboxylic Acid Methyl Ester; Methyl 4-tert-Butylcyclohexanecarboxylate; Methyl trans-4-tert-Butylcyclohexanecarboxylate; 4-(1,1-Dimethylethyl)cyclohexanecarboxylic Acid Methyl Ester; Methyl 4-(tert-Butyl)cyclohexanecarboxylate; 4-tert-Butylcyclohexanecarboxylic Acid Methyl Ester; Menthyl Carboxylate Derivative; NSC 163045
EINECS	Contact for details

Quality Control

Our 4α-tert-Butylcyclohexane-1α-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Isomeric Purity (cis/trans ratio)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.