Description

3-(5-Nitrothiophen-2-Yl)Acrylic Acid is a specialized nitro-substituted thiophene acrylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its conjugated structure, which makes it a versatile intermediate for creating complex molecules with tailored electronic and optical properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, functional materials, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting various therapeutic areas.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the nitro-thiophene moiety is integral to biological activity.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments due to its ability to influence color and lightfastness properties.
• Ligand & Catalyst Development: Useful for constructing complex ligands for metal-organic frameworks (MOFs) or catalysts in asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical reactions in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	3-(5-Nitrothiophen-2-Yl)Acrylic Acid
CAS No.	17163-22-3
Molecular Formula	C7H5NO4S
Molecular Weight	199.18 g/mol
Synonyms	3-(5-Nitro-2-thienyl)acrylic acid; 2-Propenoic acid, 3-(5-nitro-2-thienyl)-; (E)-3-(5-Nitrothiophen-2-yl)acrylic acid; 5-Nitro-2-thiopheneacrylic acid; trans-3-(5-Nitro-2-thienyl)acrylic acid; β-(5-Nitro-2-thienyl)acrylic acid; NSC 163022
EINECS	Contact for details

Quality Control

Our 3-(5-Nitrothiophen-2-Yl)Acrylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.