Description

1-(Chloro-(2-Methylpropoxy)Phosphoryl)Oxy-2-Methyl-Propane is a specialized organophosphorus compound with the CAS number 17158-87-1. This chemical serves as a critical intermediate and reagent in advanced synthetic chemistry, valued for its unique phosphorylating and chlorinating properties. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and nucleotide analogs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Acts as a precursor for phosphorus-containing ligands used in homogeneous catalysis.
• Flame Retardant Synthon: Intermediate in the manufacture of organophosphate-based flame retardant additives.
• Chemical Research & Development: A versatile reagent for phosphorylation and introducing the P-Cl functional group in novel compound libraries.
• Polymer Modification: Employed to introduce phosphonate groups into polymer chains for enhanced properties.

Basic Information

Product Name	1-(Chloro-(2-Methylpropoxy)Phosphoryl)Oxy-2-Methyl-Propane
CAS No.	17158-87-1
Molecular Formula	C8H18ClO3P
Molecular Weight	228.65 g/mol
Synonyms	Chlorodiisopropylphosphite; Diisopropyl chlorophosphite; Diisopropyl phosphorochloridite; Phosphorochloridous acid, bis(1-methylethyl) ester; Chlorobis(1-methylethoxy)phosphine; Isopropyl phosphorochloridite; Bis(isopropoxy)chlorophosphine
EINECS	241-200-1

Quality Control

Our 1-(Chloro-(2-Methylpropoxy)Phosphoryl)Oxy-2-Methyl-Propane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Chloride Content (Titration)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.