Description

3-Methyl-4-Isoxazolecarboxylic Acid is a versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its functionalized isoxazole ring, which serves as a key precursor in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of modern pesticides, herbicides, and fungicides, where the isoxazole moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific thermal or optical properties.
• Chemical Biology & Proteomics: Utilized as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Methyl-4-Isoxazolecarboxylic Acid
CAS No.	17153-20-7
Molecular Formula	C5H5NO3
Molecular Weight	127.10 g/mol
Synonyms	4-Isoxazolecarboxylic acid, 3-methyl-; 3-Methylisoxazole-4-carboxylic acid; 3-Methyl-1,2-oxazole-4-carboxylic acid; 3-Methyl-4-carboxyisoxazole; NSC 403697; AI3-52266; 3-Methyl-4-isoxazolylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-4-Isoxazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is moisture-sensitive; ensure the container is kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.