Description

2-Deoxy-5-o-(4-Phenylbenzoyl)-D-Erythro-Pentofuranose is a specialized nucleoside derivative and a key protected intermediate in synthetic organic chemistry. This compound matters for its critical role in the controlled synthesis of modified nucleosides and oligonucleotides, where precise functional group protection is essential. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and novel therapeutic nucleic acids.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Oligonucleotide Synthesis: Used as a protected monomer in the solid-phase synthesis of modified DNA/RNA strands for research and therapeutic applications.
• Medicinal Chemistry Research: Serves as a key starting material for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Bioconjugation: Acts as a functionalized precursor for creating labeled nucleosides used in diagnostic assays and imaging probes.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring protected sugar moieties.

Basic Information

Product Name	2-Deoxy-5-o-(4-Phenylbenzoyl)-D-Erythro-Pentofuranose
CAS No.	17117-72-5
Molecular Formula	C24H22O6
Molecular Weight	406.43 g/mol
Synonyms	5-O-(4-Biphenylcarbonyl)-2-deoxy-D-erythro-pentofuranose; 2-Deoxy-5-O-(4-phenylbenzoyl)-D-ribofuranose; 1,2-Dideoxy-5-O-(4-phenylbenzoyl)-D-ribofuranose; 5-O-(p-Phenylbenzoyl)-2-deoxy-D-ribofuranose; 2-Deoxy-5-O-(4-biphenylcarbonyl)-D-erythro-pentofuranose; D-erythro-Pentofuranose, 2-deoxy-5-O-(4-phenylbenzoyl)-
EINECS	Contact for details

Quality Control

Our 2-Deoxy-5-o-(4-Phenylbenzoyl)-D-Erythro-Pentofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.