Description

(4S,5S)-4-Methyl-5-Phenyl-2-Oxazolidinone CAS NO 17097-67-5 is a high-purity, chiral oxazolidinone derivative widely recognized as a versatile chiral auxiliary and building block in asymmetric synthesis. Its value lies in enabling the stereoselective construction of complex molecules, which is critical for developing pharmaceuticals and fine chemicals with high enantiomeric purity. This compound is essential for research institutions, process development chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• As a chiral auxiliary in Evans-type aldol reactions for the asymmetric synthesis of β-hydroxy carbonyl compounds.
• Key starting material or intermediate in the production of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Building block for the synthesis of novel ligands and catalysts used in enantioselective transformations.
• Intermediate in the research and development of agrochemicals, such as herbicides and fungicides with specific stereochemistry.
• Used in academic and industrial R&D for methodology development in organic and medicinal chemistry.
• Precursor for synthesizing other specialty fine chemicals and advanced materials requiring precise stereocontrol.

Basic Information

Product Name	(4S,5S)-4-Methyl-5-Phenyl-2-Oxazolidinone
CAS No.	17097-67-5
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(4S,5S)-(-)-4-Methyl-5-phenyl-2-oxazolidinone; (4S-cis)-4-Methyl-5-phenyl-2-oxazolidinone; (S,S)-4-Methyl-5-phenyloxazolidin-2-one; Evans Auxiliary; (S,S)-Evans Oxazolidinone; L-793,422; (4S,5S)-4-Methyl-5-phenyl-1,3-oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (4S,5S)-4-Methyl-5-Phenyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	87 - 91 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation ([α]D20)	-70° to -76° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.