Description

2-Acetylmalonic Acid Dimethyl Ester is a versatile and high-purity chemical building block essential for advanced organic synthesis. This compound matters as a key precursor for constructing complex heterocyclic structures and fine-tuning molecular properties in active pharmaceutical ingredients. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new compounds and process optimization.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive β-ketoester functionality.
• Organic Synthesis Building Block: Employed in Claisen condensations and other carbon-carbon bond-forming reactions to construct complex molecular architectures.
• Fine Chemical Production: Serves as a starting material for the manufacture of dyes, flavors, and fragrances.
• Academic & Industrial Research: Utilized in method development and exploratory chemistry for new material discovery.

Basic Information

Product Name	2-Acetylmalonic Acid Dimethyl Ester
CAS No.	17094-36-9
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	Dimethyl 2-Acetylmalonate; Dimethyl Acetylpropanedioate; Acetylmalonic Acid Dimethyl Ester; 2-Acetylpropanedioic Acid Dimethyl Ester; Methyl 3-Oxoglutarate; 3-Oxoglutaric Acid Dimethyl Ester; Propanedioic acid, acetyl-, dimethyl ester
EINECS	241-159-3

Quality Control

Our 2-Acetylmalonic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.