Description

(8S)-7,8,8A,9-Tetrahydro-8-Hydroxy-3,5,8Aα-Trimethylnaphtho[2,3-B]Furan-4(6H)-One is a high-purity, stereochemically defined organic compound of significant interest in advanced chemical synthesis. This molecule serves as a critical chiral intermediate or building block for the development of complex pharmaceuticals and fine chemicals. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise molecular architecture for their synthetic pathways.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, or plant growth regulators with specific stereochemical activity.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, flavors, fragrances, and advanced material precursors.
• Academic & R&D: Serves as a standard or starting material in methodological studies for organic chemistry, catalysis, and asymmetric synthesis.
• Process Development: Employed in scaling up and optimizing synthetic routes for commercial manufacturing under cGMP conditions.

Basic Information

Product Name	(8S)-7,8,8A,9-Tetrahydro-8-Hydroxy-3,5,8Aα-Trimethylnaphtho[2,3-B]Furan-4(6H)-One
CAS No.	17015-43-9
Molecular Formula	C₁₇H₂₂O₃
Molecular Weight	274.35 g/mol
Synonyms	(8S)-8-Hydroxy-3,5,8aα-trimethyl-7,8,8a,9-tetrahydro-6H-naphtho[2,3-b]furan-4-one; (8S)-8-Hydroxy-3,5,8a-trimethyl-7,8,8a,9-tetrahydro-6H-naphtho[2,3-b]furan-4-one; 8-Hydroxy-3,5,8aα-trimethyl-7,8,8a,9-tetrahydro-6H-naphtho[2,3-b]furan-4-one (8S)-; Naphtho[2,3-b]furan-4(6H)-one, 7,8,8a,9-tetrahydro-8-hydroxy-3,5,8aα-trimethyl-, (8S)-; (8S)-form of the above compound.
EINECS	Contact for details

Quality Control

Our (8S)-7,8,8A,9-Tetrahydro-8-Hydroxy-3,5,8Aα-Trimethylnaphtho[2,3-B]Furan-4(6H)-One is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.