Description

(2R,3R)-(-)-Epoxysuccinic Acid is a high-purity, chiral epoxide derivative of succinic acid, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry is essential for imparting specific three-dimensional structure and biological activity to target molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, enzyme inhibitors, and other active pharmaceutical ingredients (APIs) where stereochemistry is crucial for efficacy.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators to enhance specificity and reduce environmental impact.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis to create other high-value chiral compounds.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor for epoxide hydrolases and other enzymes to investigate metabolic pathways.
• Fine Chemical Production: Intermediate for specialty polymers, advanced materials, and complex natural product analogs requiring precise stereocontrol.

Basic Information

Product Name	(2R,3R)-(-)-Epoxysuccinic Acid
CAS No.	17015-08-6
Molecular Formula	C4H4O5
Molecular Weight	132.07 g/mol
Synonyms	(-)-trans-2,3-Epoxysuccinic Acid; (2R,3R)-2,3-Epoxysuccinic Acid; L-(-)-Epoxysuccinic Acid; (2R,3R)-(-)-2,3-Epoxybutanedioic Acid; trans-(-)-Epoxysuccinic Acid; (R,R)-(-)-Epoxysuccinic Acid; 2,3-Epoxy-(R,R)-succinic Acid; L-tartaric acid epoxide
EINECS	Contact for details

Quality Control

Our (2R,3R)-(-)-Epoxysuccinic Acid is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.