Description

α-Boc-γ-Z-(Dl)-Diaminobutyric Acid is a protected diaminobutyric acid derivative, serving as a crucial chiral building block in advanced organic synthesis. Its value lies in providing a versatile, orthogonally protected scaffold for the controlled introduction of the diaminobutyric acid moiety, essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the diaminobutyric acid (Dab) residue with orthogonal Boc and Z (Cbz) protection.
• Research & Development: Serves as a critical reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Conjugate Synthesis: Facilitates the creation of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive amine handles.
• Chemical Biology Probes: Employed in the design and synthesis of probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis: A foundational material for contract research and manufacturing organizations (CROs/CMOs) producing custom, high-value compounds for clients.

Basic Information

Product Name	α-Boc-γ-Z-(Dl)-Diaminobutyric Acid
CAS No.	16947-89-0
Molecular Formula	C₁₆H₂₂N₂O₆
Molecular Weight	338.36 g/mol
Synonyms	Boc-Dab(Z)-OH; (DL)-2-[(tert-Butoxycarbonyl)amino]-4-[(benzyloxycarbonyl)amino]butanoic Acid; Nα-Boc-Nγ-Cbz-DL-2,4-Diaminobutyric Acid; Nα-Boc-Nγ-Z-DL-α,γ-Diaminobutyric Acid; tert-Butyl N-[1-[(benzyloxycarbonyl)amino]-3-carboxypropyl]carbamate; Boc-DL-Dab(Z)-OH; DL-2,4-Diaminobutyric Acid, Nα-Boc, Nγ-Z derivative; N-Boc-N'-Cbz-DL-2,4-diaminobutyric acid
EINECS	Contact for details

Quality Control

Our α-Boc-γ-Z-(Dl)-Diaminobutyric Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.