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N4-(2-Acetylamino-3-O,4-O,6-o-Triacetyl-2-Deoxy-β-D-Glucopyranosyl)-N2-Trifluoroacetyl-L-Asparagine Ethyl Ester CAS NO 16907-93-0
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CAS No.:16907-93-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
N4-(2-Acetylamino-3-O,4-O,6-o-Triacetyl-2-Deoxy-β-D-Glucopyranosyl)-N2-Trifluoroacetyl-L-Asparagine Ethyl Ester is a sophisticated, protected carbohydrate-amino acid conjugate, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex glycopeptides and glycoconjugates, enabling precise research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on glycoscience, drug discovery, and the synthesis of biologically active molecules.
Application
- Glycopeptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of complex glycopeptides, mimicking natural post-translational modifications.
- Glycoconjugate Development: Used in the preparation of carbohydrate-based vaccines, diagnostic agents, and targeted drug delivery systems.
- Medicinal Chemistry Research: Serves as a building block for creating libraries of novel compounds to explore structure-activity relationships (SAR) in drug discovery programs.
- Biochemical Tool Development: Employed in the synthesis of enzyme substrates, inhibitors, or probes for studying glycosylation processes and carbohydrate-protein interactions.
- Academic & Industrial R&D: Essential for fundamental research in glycoscience and for process development in the scale-up of therapeutic candidates.
Basic Information
| Product Name | N4-(2-Acetylamino-3-O,4-O,6-o-Triacetyl-2-Deoxy-β-D-Glucopyranosyl)-N2-Trifluoroacetyl-L-Asparagine Ethyl Ester |
| CAS No. | 16907-93-0 |
| Molecular Formula | C₂₅H₃₄F₃N₃O₁₃ |
| Molecular Weight | 665.55 g/mol |
| Synonyms | N4-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-N2-trifluoroacetyl-L-asparagine ethyl ester; N2-Trifluoroacetyl-N4-(3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-glucopyranosyl)-L-asparagine ethyl ester; β-D-GlcpNAc(Ac)3-Asn(TFA)-OEt; TFA-Asn(β-GlcNAc(Ac)3)-OEt; Glycosylated Asparagine Derivative; Protected GlcNAc-Asparagine Conjugate; Fmoc-Asn(GlcNAc(Ac)3)-OH precursor (related); Glycopeptide Building Block |
| EINECS | Contact for details |
Quality Control
Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of N4-(2-Acetylamino-3-O,4-O,6-o-Triacetyl-2-Deoxy-β-D-Glucopyranosyl)-N2-Trifluoroacetyl-L-Asparagine Ethyl Ester is characterized using advanced analytical techniques (HPLC, NMR, MS) to confirm identity, purity, and stability. Certificates of Analysis (COA) with detailed specifications are available upon request. We adhere to GMP principles for handling high-value research chemicals to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up projects.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the label or CoA. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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