Description

(2-Methyl-1,2,3,4-Tetrahydroisoquinolin-3-Yl)Methanol is a versatile tetrahydroisoquinoline derivative, a key structural motif in medicinal chemistry. This compound serves as a crucial chiral building block and synthetic intermediate for the development of active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex organic molecules, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those containing the privileged tetrahydroisoquinoline scaffold.
• Chiral Building Block: Used in asymmetric synthesis to introduce stereochemical complexity into target molecules, leveraging its chiral center for the production of enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Potential intermediate in the development of advanced pesticides and herbicides due to its heterocyclic structure.
• Ligand and Catalyst Development: Can be utilized to synthesize novel ligands for metal-catalyzed reactions or organocatalysts.
• Fine Chemical Production: Serves as a specialized intermediate in the custom synthesis of high-value, low-volume fine chemicals.

Basic Information

Product Name	(2-Methyl-1,2,3,4-Tetrahydroisoquinolin-3-Yl)Methanol
CAS No.	16880-87-8
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	3-(Hydroxymethyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-Methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanol; (2-Methyl-3,4-dihydro-1H-isoquinolin-3-yl)methanol; 3-Hydroxymethyl-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-Methyl-1,2,3,4-tetrahydroisoquinoline-3-methanol
EINECS	Contact for details

Quality Control

Our (2-Methyl-1,2,3,4-Tetrahydroisoquinolin-3-Yl)Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.